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Tribromsalan

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Tribromsalan is a widely used ingredient in cosmetics, personal care, and skincare formulations. Depending on its function, it may serve as a moisturizer, preservative, emulsifier, or active ingredient to enhance the overall effectiveness and performance of a product.

Tribromsalan (Wikipedia)

Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide.

Salicylanilide
Names
Preferred IUPAC name
2-Hydroxy-N-phenylbenzamide
Other names
2-Hydroxybenzanilide
Identifiers
3D model (JSmol)
1108135
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.001.571 Edit this at Wikidata
EC Number
  • 201-727-8
KEGG
UNII
  • InChI=1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) ☒N
    Key: WKEDVNSFRWHDNR-UHFFFAOYSA-N ☒N
  • InChI=1/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16)
    Key: WKEDVNSFRWHDNR-UHFFFAOYAI
  • C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O
Properties
C13H11NO2
Molar mass 213.236 g·mol−1
Appearance White to off-white crystalline solid
Melting point 136 to 138 °C (277 to 280 °F; 409 to 411 K)
Hazards
GHS labelling:
GHS07: Exclamation markGHS09: Environmental hazard
Warning
H315, H319, H335, H400
P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P391, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Derivatives of salicylanilide have a variety of pharmacological uses. Chlorinated derivatives including niclosamide, oxyclozanide, and rafoxanide are used as anthelmintics, especially as flukicides. Brominated derivatives including dibromsalan, metabromsalan, and tribromsalan are used as topical antibacterials and antifungals.

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