Tetrasodium etidronate

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Tetrasodium etidronate is a widely used ingredient in cosmetics, personal care, and skincare formulations. Depending on its function, it may serve as a moisturizer, preservative, emulsifier, or active ingredient to enhance the overall effectiveness and performance of a product.

Etidronic acid, also known as etidronate, is a non-nitrogenous bisphosphonate used as a medication, detergent, water treatment, and cosmetic.

Etidronic acid
Clinical data
Trade namesDidronel, others
Other names1-Hydroxyethylidene-1,1-diphosphonic acid; HEDP
AHFS/Drugs.comInternational Drug Names
License data
Routes of
administration
Oral, intravenous
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability3%
MetabolismNil
Elimination half-life1 to 6 hours
ExcretionRenal and fecal
Identifiers
  • (1-Hydroxyethan-1,1-diyl)bis(phosphonic acid)
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.018.684 Edit this at Wikidata
Chemical and physical data
FormulaC2H8O7P2
Molar mass206.027 g·mol−1
3D model (JSmol)
  • O=P(O)(O)C(O)(C)P(=O)(O)O
  • InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9) checkY
  • Key:DBVJJBKOTRCVKF-UHFFFAOYSA-N checkY
  (verify)

It was patented in 1966 and approved for medical use in 1977.

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