This site uses cookies to offer you a better browsing experience. By browsing this website, you agree to our use of cookies.

Salicylic acid

ALL0-9ABCDEFGHIJKLMNOPQRSTUVWXYZ
« Back to Glossary Index

Salicylic acid is a widely used ingredient in cosmetics, personal care, and skincare formulations. Depending on its function, it may serve as a moisturizer, preservative, emulsifier, or active ingredient to enhance the overall effectiveness and performance of a product.

Salicylic acid (Wikipedia)

Salicylic acid is an organic compound with the formula HOC6H4COOH. A colorless (or white), bitter-tasting solid, it is a precursor to and a metabolite of acetylsalicylic acid (aspirin). It is a plant hormone, and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen. The name is from Latin salix for willow tree, from which it was initially identified and derived. It is an ingredient in some anti-acne products. Salts and esters of salicylic acid are known as salicylates.

Salicylic acid
Skeletal formula of salicylic acid
Skeletal formula of salicylic acid
Ball-and-stick model of salicylic acid
Ball-and-stick model of salicylic acid
Salicylic acid
Salicylic acid
Names
Preferred IUPAC name
2-Hydroxybenzoic acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.000.648 Edit this at Wikidata
EC Number
  • 200-712-3
KEGG
RTECS number
  • VO0525000
UNII
  • InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10) checkY
    Key: YGSDEFSMJLZEOE-UHFFFAOYSA-N checkY
  • InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
    Key: YGSDEFSMJLZEOE-UHFFFAOYAQ
  • O=C(O)c1ccccc1O
Properties
C7H6O3
Molar mass 138.122 g/mol
Appearance Colorless to white crystalline powder
Odor Odorless
Density 1.443 g/cm3 (20 °C)
Melting point 158.6 °C (317.5 °F; 431.8 K)
Boiling point 211 °C (412 °F; 484 K)
at 20 mmHg
Sublimes at 76 °C
  • 1.24 g/L (0 °C)
  • 2.48 g/L (25 °C)
  • 4.14 g/L (40 °C)
  • 17.41 g/L (75 °C)
  • 77.79 g/L (100 °C)
Solubility Soluble in ether, CCl4, benzene, propanol, acetone, ethanol, oil of turpentine, toluene
Solubility in benzene
  • 0.46 g/100 g (11.7 °C)
  • 0.775 g/100 g (25 °C)
  • 0.991 g/100 g (30.5 °C)
  • 2.38 g/100 g (49.4 °C)
  • 4.4 g/100 g (64.2 °C)
Solubility in chloroform
  • 2.22 g/100 mL (25 °C)
  • 2.31 g/100 mL (30.5 °C)
Solubility in methanol
  • 40.67 g/100 g (−3 °C)
  • 62.48 g/100 g (21 °C)
Solubility in olive oil 2.43 g/100 g (23 °C)
Solubility in acetone 39.6 g/100 g (23 °C)
log P 2.26
Vapor pressure 10.93 mPa
Acidity (pKa)
  1. 2.97 (25 °C)
  2. 13.82 (20 °C)
UV-vis (λmax) 210 nm, 234 nm, 303 nm (4 mg/dL in ethanol)
−72.23·10−6 cm3/mol
1.565 (20 °C)
2.65 D
Thermochemistry
−589.9 kJ/mol
-3.025 MJ/mol
Pharmacology
A01AD05 (WHO) B01AC06 (WHO) D01AE12 (WHO) N02BA01 (WHO) S01BC08 (WHO)
Hazards
Occupational safety and health (OHS/OSH):
Eye hazards
 Severe irritation
Skin hazards
 Mild irritation
GHS labelling:
GHS05: Corrosive GHS07: Exclamation mark
Danger
H302, H318
P280, P305+P351+P338
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g. chloroformFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
2
1
0
Flash point 157 °C (315 °F; 430 K)
closed cup
540 °C (1,004 °F; 813 K)
Lethal dose or concentration (LD, LC):
480 mg/kg (mice, oral)
Safety data sheet (SDS) MSDS
Related compounds
Related compounds
 Methyl salicylate,
Benzoic acid,
Phenol, Aspirin,
4-Hydroxybenzoic acid,
Magnesium salicylate,
Choline salicylate,
Bismuth subsalicylate,
Sulfosalicylic acid,
Salicylate synthase
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
« Back to Glossary Index
This entry was posted in . Bookmark the permalink.
adminWonk

Ben McPherson is a self-taught digital artist renowned for his vibrant and innovative artworks. With a solid foundation in information technology, he has expertly merged his technical acumen with his artistic pursuits. Since the 1990s, he's been a prevalent figure in the marketing IT sector, working with various companies across the Tri-State area. His unique background allows him to infuse his digital art with complexity and a deep understanding of modern technology, setting his work apart in the digital art scene.