Methylisothiazolinone is a widely used ingredient in cosmetics, personal care, and skincare formulations. Depending on its function, it may serve as a moisturizer, preservative, emulsifier, or active ingredient to enhance the overall effectiveness and performance of a product.
Methylisothiazolinone (/ˌmɛθəlˌaɪsoʊˌθaɪ.əˈzoʊlɪnoʊn/), MIT, or MI, is the organic compound with the formula S(CH)2C(O)NCH3. It is a white solid. Isothiazolinones, a class of heterocycles, are used as biocides in numerous personal care products and other industrial applications. MIT and related compounds have attracted much attention for their allergenic properties, e.g. contact dermatitis.
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Names | |
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Preferred IUPAC name
2-Methyl-1,2-thiazol-3(2H)-one | |
Other names
2-Methylisothiazol-3(2H)-one
2-Methyl-4-isothiazolin-3-one | |
Identifiers | |
3D model (JSmol)
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Abbreviations | MIT, MI |
606203 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.018.399 |
EC Number |
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PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C4H5NOS | |
Molar mass | 115.1 g/mol |
Appearance | white solid |
Hazards | |
GHS labelling: | |
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Danger | |
H301, H311, H314, H317, H330, H410 | |
P260, P261, P264, P270, P271, P272, P273, P280, P284, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P320, P321, P322, P330, P333+P313, P361, P363, P391, P403+P233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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