Homosalate
Homosalate is a widely used ingredient in cosmetics, personal care, and skincare formulations. Depending on its function, it may serve as a moisturizer, preservative, emulsifier, or active ingredient to enhance the overall effectiveness and performance of a product.
Homosalate is an organic compound used in some sunscreens. It is made by the Fischer–Speier esterification of salicylic acid and 3,3,5-trimethylcyclohexanol, the latter being a hydrogenated derivative of isophorone. Contained in 45% of U.S. sunscreens, it is used as a chemical UV filter. The salicylic acid portion of the molecule absorbs ultraviolet rays with a wavelength from 295 nm to 315 nm, protecting the skin from sun damage. The hydrophobic trimethyl cyclohexyl group provides greasiness that prevents it from dissolving in water.
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| Names | |
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| IUPAC name
3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate
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| Other names
Homosalate
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
| ECHA InfoCard | 100.003.874 |
| KEGG | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C16H22O3 | |
| Molar mass | 262.349 g·mol−1 |
| Density | 1.05 g/cm3 (20 °C) |
| Melting point | < -20 °C |
| Boiling point | 181–185 °C (358–365 °F; 454–458 K) |
| 0.4 mg/L | |
| Hazards | |
| Flash point | 171 °C (340 °F; 444 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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