Glucose oxidase
Glucose oxidase is a widely used ingredient in cosmetics, personal care, and skincare formulations. Depending on its function, it may serve as a moisturizer, preservative, emulsifier, or active ingredient to enhance the overall effectiveness and performance of a product.
The glucose oxidase enzyme (GOx or GOD) also known as notatin (EC number 1.1.3.4) is an oxidoreductase that catalyses the oxidation of glucose to hydrogen peroxide and D-glucono-δ-lactone. This enzyme is produced by certain species of fungi and insects and displays antibacterial activity when oxygen and glucose are present.
| Glucose oxidase | |||||||||
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 Structure of glucose oxidase dimer (dark and light blue) complexed with FAD (salmon) and glycans (aquamarine) from Penicillium amagasakiense. | |||||||||
| Identifiers | |||||||||
| EC no. | 1.1.3.4 | ||||||||
| CAS no. | 9001-37-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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-alpha-D-Glucose.svg) | |
| Names | |
|---|---|
| Other names
Oxidase, glucose
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| Identifiers | |
| ChemSpider |
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| ECHA InfoCard | 100.029.625 |
| EC Number |
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| E number | E1102 (additional chemicals) |
| KEGG | |
| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| (C6H10O5)n | |
| Molar mass | variable |
| Appearance | white or yellow powder |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Glucose oxidase is widely used for the determination of free glucose in body fluids (medical testing), in vegetal raw material, and in the food industry. It also has many applications in biotechnologies, typically enzyme assays for biochemistry including biosensors in nanotechnologies. It was first isolated by Detlev Müller in 1928 from Aspergillus niger.
