Ethoxydiglycol

Ethoxydiglycol is a water-soluble solvent and viscosity-reducing agent commonly used in skincare and cosmetic formulations. Also known as diethylene glycol monoethyl ether, it enhances the penetration of active ingredients into the skin, improving their effectiveness. This clear, odorless liquid is particularly valued for its ability to dissolve both water- and oil-soluble substances, making it a versatile ingredient in serums, creams, and other topical products. Due to its low irritation potential, it is widely used in dermatological treatments, including those targeting hyperpigmentation, acne, and aging. Its inclusion in formulations helps stabilize and evenly distribute ingredients, ensuring a smooth, lightweight texture. While generally considered safe in regulated concentrations, excessive amounts may cause irritation, reinforcing the importance of proper formulation in cosmetic science.

Ethoxydiglycol (Wikipedia)

2-(2-Ethoxyethoxy)ethanol, also known under many trade names, is the organic compound with the formula CH₃CH₂OCH₂CH₂OCH₂CH₂OH. It is a colorless liquid. It is a popular solvent for commercial applications. It is produced by the ethoxylation of ethanol (CH₃CH₂OH).

2-(2-Ethoxyethoxy)ethanol

Names
Preferred IUPAC name 2-(2-Ethoxyethoxy)ethan-1-ol
Other names 3,6-dioxa-1-octanol, DEGEE, diethylene glycol monoethyl ether, ethoxydiglycol, Carbitol, Carbitol Cellosolve, Transcutol, Dioxitol, Polysolv DE, Dowanal DE
Identifiers
CAS Number	111-90-0 Y
3D model (JSmol)	Interactive image Interactive image
ChEBI	CHEBI:40572 Y
ChEMBL	ChEMBL1230841
ChemSpider	13839107 Y
ECHA InfoCard	100.003.563
KEGG	D08904 Y
PubChem CID	8146
RTECS number	KK8750000
UNII	A1A1I8X02B Y
CompTox Dashboard (EPA)	DTXSID2021941
InChI InChI=1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3 Y Key: XXJWXESWEXIICW-UHFFFAOYSA-N Y InChI=1/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3 Key: XXJWXESWEXIICW-UHFFFAOYAC
SMILES CCOCCOCCO OCCOCCOCC
Properties
Chemical formula	C6H14O3
Molar mass	134.175 g·mol−1
Melting point	−76 °C (−105 °F; 197 K)
Boiling point	196 to 202 °C (385 to 396 °F; 469 to 475 K)
Hazards
Flash point	96 °C (205 °F; 369 K)
Autoignition temperature	204 °C (399 °F; 477 K)
Safety data sheet (SDS)	External MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references