DMAE

Dimethylaminoethanol (DMAE) is an organic compound known for its skin-firming and anti-aging properties. Naturally found in small amounts in the human body and certain fish like salmon and sardines, DMAE is widely used in skincare for its ability to improve skin elasticity, reduce fine lines, and promote a more lifted appearance.

One of DMAE’s primary functions is to enhance muscle tone by stabilizing cell membranes and reducing oxidative stress. This leads to a temporary tightening effect, making the skin appear firmer and more contoured. Additionally, its antioxidant properties help protect the skin from free radical damage, slowing down the signs of aging.

DMAE is commonly found in serums, creams, and anti-aging formulations designed to improve skin firmness and texture. While it provides noticeable short-term lifting effects, long-term use may also contribute to overall skin resilience and smoothness. Some individuals may experience mild irritation or tingling when first using DMAE, so it is often recommended to start with lower concentrations and gradually increase usage.

Due to its ability to promote a youthful, toned appearance, DMAE is a popular ingredient in skincare products aimed at mature skin, particularly those targeting sagging and loss of firmness.

DMAE (Wikipedia)

Dimethylethanolamine (DMAE or DMEA) is an organic compound with the formula (CH₃)₂NCH₂CH₂OH. It is bifunctional, containing both a tertiary amine and primary alcohol functional groups. It is a colorless viscous liquid. It is used in skin care products for improving skin tone and also taken orally as a nootropic. It is prepared by the ethoxylation of dimethylamine.

Dimethylethanolamine

Names
Preferred IUPAC name 2-(Dimethylamino)ethan-1-ol
Other names Deanol Dimethyl ethanolamine Dimethylaminoethanol N,N-Dimethylaminoethanol N,N-Dimethylethanolamine
Identifiers
CAS Number	108-01-0 Y
3D model (JSmol)	Interactive image
Abbreviations	DMAE, DMEA
Beilstein Reference	1209235
ChEBI	CHEBI:271436 N
ChEMBL	ChEMBL1135 N
ChemSpider	13854944 N
ECHA InfoCard	100.003.221
EC Number	203-542-8
KEGG	D07777 N
MeSH	Deanol
PubChem CID	7902
RTECS number	KK6125000
UNII	2N6K9DRA24 Y
UN number	2051
CompTox Dashboard (EPA)	DTXSID2020505
InChI InChI=1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3 N Key: UEEJHVSXFDXPFK-UHFFFAOYSA-N N
SMILES CN(C)CCO
Properties
Chemical formula	C4H11NO
Molar mass	89.138 g·mol−1
Appearance	Colourless liquid
Odor	Fishy, ammoniacal
Density	890 mg mL−1
Melting point	−59.00 °C; −74.20 °F; 214.15 K
Boiling point	134.1 °C; 273.3 °F; 407.2 K
log P	−0.25
Vapor pressure	816 Pa (at 20 °C)
Acidity (pKa)	9.23 (at 20 °C)
Basicity (pKb)	4.77 (at 20 °C)
Refractive index (nD)	1.4294
Pharmacology
ATC code	N06BX04 (WHO)
Hazards
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H226, H302, H312, H314, H332
Precautionary statements	P280, P305+P351+P338, P310
Flash point	39 °C (102 °F; 312 K)
Explosive limits	1.4–12.2%
Lethal dose or concentration (LD, LC):
LD50 (median dose)	1.214 g/kg (dermal, rabbit) 2 g/kg (oral, rat)
Related compounds
Related alkanols	N-Methylethanolamine Diethylethanolamine Diethanolamine N,N-Diisopropylaminoethanol Methyl diethanolamine Triethanolamine Bis-tris methane
Related compounds	Diethylhydroxylamine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references