Calcium thioglycolate

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Calcium thioglycolate is a widely used ingredient in cosmetics, personal care, and skincare formulations. Depending on its function, it may serve as a moisturizer, preservative, emulsifier, or active ingredient to enhance the overall effectiveness and performance of a product.

Thioglycolic acid (TGA) is the organic compound HSCH2CO2H. TGA is often called mercaptoacetic acid (MAA). It contains both a thiol (mercaptan) and carboxylic acid functional groups. It is a colorless liquid with a strongly unpleasant odor. TGA is miscible with polar organic solvents.

Thioglycolic acid
Space-filling model of thioglycolic acid
Space-filling model of thioglycolic acid
Names
Preferred IUPAC name
Sulfanylacetic acid
Other names
2-Sulfanylacetic acid
2-Mercaptoacetic acid
Acetyl mercaptan
Mercaptoacetate
Mercaptoacetic acid
Thioglycolic acid
Thiovanic acid
Identifiers
3D model (JSmol)
506166
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.000.616 Edit this at Wikidata
EC Number
  • 200-677-4
101048
KEGG
RTECS number
  • AI5950000
UNII
  • InChI=1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4) checkY
    Key: CWERGRDVMFNCDR-UHFFFAOYSA-N checkY
  • InChI=1/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)
    Key: CWERGRDVMFNCDR-UHFFFAOYAP
  • C(C(=O)O)S
Properties
C2H4O2S
Molar mass 92.11 g·mol−1
Appearance colorless, clear liquid
Odor strong, disagreeable
Density 1.32 g/cm3
Melting point −16 °C (3 °F; 257 K)
Boiling point 96 °C (205 °F; 369 K) at 5 mmHg
miscible
Vapor pressure 10 mmHg (17.8 °C)
−50.0·10−6 cm3/mol
Hazards
GHS labelling:[1]
GHS05: CorrosiveGHS06: Toxic
H301+H311+H331, H314
P260, P261, P262, P264, P264+P265, P270, P271, P272, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P320, P321, P330, P333+P317, P361+P364, P362+P364, P363, P403+P233, P405, P501
Flash point > 110 °C; 230 °F; 383 K
Explosive limits 5.9%
NIOSH (US health exposure limits):
PEL (Permissible)
none
REL (Recommended)
TWA 1 ppm (4 mg/m3) [skin]
IDLH (Immediate danger)
N.D.
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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